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Neonatal Equine Herpesvirus Type 1 Infection on a Thoroughbred Breeding Farm
Authors:Michael J. Murray  Fabio del  Piero   Stuart C. Jeffrey  Michael S. Davis  Martin O. Furr  Edward J. Dubovi  John A. Mayo
Affiliation:Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Leesburg, VA;New York State Veterinary Diagnostic Laboratory, Cornell University, Ithaca, NY;Mayo &Rofe Equine Clinic, Middleburg, VA
Abstract:Of 17 foals born on a Thoroughbred breeding farm between March and April 1995, infection with equine herpesvirus type 1 (EHV-1) was associated with neonatal morbidity in 5 foals, 3 of which died or were euthanized. Morbidity and mortality were associated with pulmonary inflammation, and EHV-1 was identified in the lungs of the 3 foals that died. All neonatal EHV-1 infections occurred in foals of mares housed in the same pasture and barn. No other clinical manifestations of EHV-1 infection (eg, abortion, neurologic disease, or respiratory disease) occurred during this outbreak. Three foals were treated with acyclovir (1 died, 2 survived), which may have influenced the clinical outcome in the surviving foals.
Keywords:Acyclovir    EHV-1    Herpesvirus    Neonatal foals    Viral infection
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