Combined Therapeutic Effect of Dietary Selenium and Vitamin Ε on Manifested Vesd Syndrome in Weaned Pigs |
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Authors: | Juhani Hakkarainen Paul Lindberg Gsta Bengtsson Lennart Jnsson |
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Institution: | 113.Department of Animal Hygiene and the Department of Pathology, College of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden ;213.the Department of Biochemistry, College of Veterinary Medicine, Helsinki, Finland ;313.the Department of Animal Hygiene, Animal Science Center, College of Veterinary Medicine, Swedish University of Agricultural Sciences, S-750 07 Uppsala, Sweden |
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Abstract: | By using a therapeutic dietary supplementation in pigs, which had developed the vitamin Ε and selenium deficiency (VESD) syndrome, the same amounts of α-tocopheryl acetate and selenium were found to be effective as under prophylactic conditions. The experiment thus supported the conclusions that the addition of 5 mg DL-α-tocopheryl acetate/kg and 135 μg selenium/kg to a diet, which contained only traces of vitamin Ε and selenium, represents a level of minimal requirement. Glutathione peroxidase activity in blood serum was used to evaluate the selenium status in pigs. A modified method for determination of tocopherol in fat tissue was described. The addition of 15 mg α-tocopheryl acetate/kg diet was demonstrated to be sufficient to maintain the tocopherol stores in body fat at an unchanged level. |
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Keywords: | dietary tocopherol selenium therapy pigs serum glutathione peroxidase tissue fat tocopherol |
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