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Antiserum to immunoglobulin A: Inhibition of cell-mediated demyelination in tissue culture |
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| Authors: | G F Winkler B G Arnason |
| Abstract: | Lymph node cells from rats immunized with sciatic nerve in Freund's adjuvant demyelinate trigeminal ganglion cultures. Rabbit antiserum to rat immunoglobulin A blocks this cytodestructive event. The antiserum may act by combining with IgA on the lymphoid cell surface, preventing the interaction of cell-bound antibody and tissue anitigen. |
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