The cardiorespiratory effects of morphine and butorphanol in horses anaesthetised under clinical conditions |
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Authors: | A M Nolan J P Chambers† G J Hale‡ |
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Institution: | Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge;?Department of Pharmacology, University of Bristol, University Walk, Bristol BS8 lTD;?Ashlands Veterinary Centre, 119 Leeds Road, Ilkley, West Yorks. LS29 8JS, UK. |
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Abstract: | Twenty-five horses admitted for minor orthopaedic or soft tissue surgery were anaesthetised with detomidine, ketamine and halothane. Heart rate, arterial blood pressure, respiratory rate, tidal volume, minute volume, blood gases and occlusion pressures were measured before and for 30 mins after intravenous (iv) injection of saline, butorphanol 0.05 mg/kg bodyweight (bwt) or morphine 0.02 or 0.05 mg/kg bwt. Drug or saline treatment induced no significant changes from pre-treatment values within a group for arterial blood pressure, heart rate, respiratory rate, arterial carbon dioxide tension, arterial oxygen tension and occlusion pressure. In conclusion, both morphine and butorphanol at the stated doses cause no adverse effects on the cardiovascular and respiratory systems of anaesthetised horses. |
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