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Scavenging effect and antispasmodic activity of the essential oil of Cyclotrichium niveum
Authors:Cetinus Senay Akkuş  Göze Ismihan  Saraç Bülent  Vural Nilüfer
Affiliation:Department of Chemistry, Faculty of Science and Literature, Cumhuriyet University, 58140 Turkey. scetinus@cumhuriyet.edu.tr
Abstract:The radical scavenging and the spasmolitic activity of Cyclotrichium niveum essential oil were evaluated in vitro. It showed an IC(50) of 1750 microg/ml on DPPH method and dose dependently (0.1, 0.5 and 1 mg/ml) inhibits the contraction induced by carbachol on rabbit bladder from 15 to 100%. Moreover, it was able to inhibit the rat ileum muscle by 30 to 100%.
Keywords:Cyclotrichium niveum   Antioxidant activity   Antispasmodic activity
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