伊扑拉芬对大鼠生长性能及性激素水平的影响

20只28日龄Sprague-Dawley(SD)大鼠等分成2组，试验组在基础日粮中添加伊扑拉芬5mg／kg，试验为期5周。结果表明：添喂伊扑拉芬后，雄性大鼠与对照组相比日增重提高38．65％，料重比降低为对照组的38．24％；腿肌的相对重量升高56．84％，脂肪的相对重量降低5．71％；血清尿素氮水平下降10．17％，谷丙转氨酶活性、碱性磷酸酶活性分别较对照组升高33．67％和43．76％，血清睾酮水平较对照组上升773．53％，腿肌RNA／DNA的比率较对照组升高10．40％。雌性大鼠与对照组相比日增重和料重比均无显著差异；腿肌的相对重量升高2．22％，脂肪的相对重量降低16．92％；血清尿素氮、谷丙转氨酶、碱性磷酸酶及雌二醇分别较对照组降低10．56％、29．05％、11．90％和23．82％，腿肌RNA／DNA较对照组降低5．75％。

Effect of Ipriflavone on the Growth Performance and Sex Hormone Level in Rats

The experiment was conducted with 20 rats of 28 days old to investigate the effect of ipri-flavone at dosage of 5 mg/kg in diet for 5 weeks. Compared with those of male control group, the body weight gain increased by 38. 82%, the average daily body weight gain increased by 38. 65% and feed intake/daily body weight gain was lowed 62. 17%; The relative percentage to the body weight of muscle increased by 56. 84%, fat relative percentage was lowed 5. 71%; The serum urea-N was low 10. 17%, but the activity of glutamic pyruvic transaminase and alkaline phosphatase and the level of testoterone increased by 33. 67% and 43. 76% and 773. 53%, respectively. The ratio of RNA/DNA of muscle increased by 10. 40%. Compared with those of female control group, there were no significant effect of ipriflavone on the average daily body gain and feed intake/daily body weight gain. The relative percentage to the body weight of muscle increased by 2. 22%, fat relative percentage was lowed 16. 92%; The activities of glutamic pyruvic transaminase and alkaline phosphatase and the level of serum urea-N and estrogen were decreased. The ratio of RNA/DNA of muscle was lowed by 5. 57%.