The protective role of ascorbic acid (vitamin C) against chlorpyrifos-induced oxidative stress in Oreochromis niloticus |
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| Authors: | Ferbal ?zkan Suna Gül Gündüz Mehmet Berk?z Arzu ?zlüer Hunt Serap Yal?n |
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| Affiliation: | Department of Basic Sciences, Faculty of Fisheries, Mersin University, Mersin, Turkey. ferbal1111@hotmail.com |
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| Abstract: | Ability of ascorbic acid (vitamin C) to attenuate oxidative damage was evaluated in liver and brain tissues of Oreochromis niloticus (O. niloticus) experimentally exposed to sublethal concentrations of chlorpyrifos (CPF). O. niloticus was exposed to sublethal concentrations of CPF at 12?μg/L (CPF1) and 24?μg/L (CPF2) for 96?h. The fish of vitamin C (Vit C) and CPF2?+?Vit C groups were fed with Vit C supplemented diet (200?mg Vit C/100?g feed). A significant increase in thiobarbituric acid-reactive substances (TBARS) level (P?
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