| PGP基因家族成员的结构和功能 |
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| 引用本文： | 李洋,刁健,郝昕,马玲. PGP基因家族成员的结构和功能[J]. 东北林业大学学报, 2021, 49(3): 126-131. DOI: 10.3969/j.issn.1000-5382.2021.03.021 |
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| 作者姓名： | 李洋 刁健 郝昕 马玲 |
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| 作者单位： | 东北林业大学,哈尔滨,150040;东北林业大学,哈尔滨,150040;东北林业大学,哈尔滨,150040;东北林业大学,哈尔滨,150040 |
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| 基金项目： | 国家重点研究发展计划项目 |
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| 摘 要： | 通过对松材线虫耐药基因家族成员Bx-pgps的基因和蛋白质结构与功能的分析,对该家族成员的耐药机制进行了分析预测。从松材线虫基因组数据库中获得了与秀丽线虫pgp基因家族成员同源的基因,分别命名为Bx-pgp1至Bx-pgp10。对其疏水性、跨膜区域和拓扑异构结构等生物学特性进行了预测。结果表明:Bx-PGPs家族成员可能具有跨膜运输功能。
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| 关 键 词： | 松材线虫 Bx-pgp基因家族 基因和蛋白质结构 生物信息学 |
Structure and Function of PGP Gene Family Members |
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| Li Yang,Diao Jian,Hao Xin,Ma Ling. Structure and Function of PGP Gene Family Members[J]. Journal of Northeast Forestry University, 2021, 49(3): 126-131. DOI: 10.3969/j.issn.1000-5382.2021.03.021 |
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| Authors: | Li Yang Diao Jian Hao Xin Ma Ling |
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| Affiliation: | (Northeast Forestry University,Harbin 150040,P.R.China) |
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| Abstract: | With the molecular biological identification of members in the Bursaphelenchus xylophilus resistance gene family Bx-pgps,and their gene and protein structure and function,we analyzed and predicted the resistance mechanism of the family members.Genes homologous to members of the pgp gene family of C.elegans were obtained from B.xylophilus genome database,and named Bx-pgp1 to Bx-pgp10,respectively.We predicted and analyzed their properties including hydrophobicity,transmembrane regions,and topologically heterogeneous structures.Analysis results showed that members of the Bx-PGPs family have transmembrane transport functions. |
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| Keywords: | Bursaphelenchus xylophilus Bx-pgp gene family Gene and protein structure Bioinformation |
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