| 环氧化酶-2与犬眼部疾病关系的研究进展 |
| |
| 引用本文： | 崔君.环氧化酶-2与犬眼部疾病关系的研究进展[J].天津农学院学报,2009,16(4):47-50. |
| |
| 作者姓名： | 崔君 |
| |
| 作者单位： | 天津农学院,动物科学系,天津,300384 |
| |
| 摘 要： | 环氧化酶-2（COX-2）因参与机体的多种病理生理过程而日益受到重视。它在眼部炎症、角膜和视网膜新生血管、青光眼、白内障、增生性玻璃体视网膜病变等许多疾病的发生发展中起着重要的介质作用。自20世纪90年代初，国外就发现环氧化酶有两种同工酶COX-1和COX-2，COX-1参与机体正常的生理功能，而COX-2则参与多种病理生理过程，包括炎症、损伤、修复、新生血管的生成及肿瘤的生长和转移，对COX-2的研究更有助于探究犬的某些眼部疾病的发生机制以及进一步完善疾病治疗手段，提高治疗效果。本文就环氧化酶-2与犬眼部疾病的关系进行论述。
|
| 关 键 词： | 环氧化酶-2 犬 眼 |
Progresses on Relationship Between Cyclooxygenase-2 and Ocular Diseases of Canines |
| |
| CUI Jun.Progresses on Relationship Between Cyclooxygenase-2 and Ocular Diseases of Canines[J].Journal of Tianjin Agricultural College,2009,16(4):47-50. |
| |
| Authors: | CUI Jun |
| |
| Institution: | CUI Jun (Department of Animal Science, Tianjin Agricultural University, Tianjin 300384, China) |
| |
| Abstract: | Cyclooxygenase-2 （COX-2）-derived prostaglandins （PGs） are attacting more and more interests because of their important pathophysiologic roles in various diseases. There are two COX isofroms, COX-1 and COX-2, which produce prostaglandins with different physiological effects. COX-2 metabolites likely play a role in both tissue remodeling and tissue damage after corneal trauma. The studies on mechanisms of COX-2 function can contribute to learning the mechanisms of the ocular diseases, improving the therapeutical measures and effects. It is elaborated the relationship between COX-2 and the ocular diseases of canine. |
| |
| Keywords: | Cyclooxygenase-2 canine ocular |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
