Biological Functions of TLRs in Mammalian Ovulation Processes |
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Authors: | JIA Sheng-jun ZHAO Jiao LI Na |
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Affiliation: | 1. Bureau of Ecological Civilization Construction, Zhongshan District, Liupanshui City, Guizhou Province, Liupanshui 553000, China;2. College of Veterinary Medicine, Yangzhou University, Yangzhou 225000, China |
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Abstract: | Toll-like receptors (TLRs) is the main category of pattern recognition receptors.It is not only expressed in classical immune cells,but also expressed in the ovary and the genital tract of a variety of mammals.It plays an important role in ovarian activities.Biological functions of TLRs in the ovulation processes is the main research content in the field of reproductive immunology because that ovulation is a core event in ovarian activities and the key to determine the success or failure of reproductive.This review will concentrate on expression and distribution of TLRs in mammalian ovary,regulation mechanisms of TLRs expression and function,and the functions and significance of the ovulation process.Then we analyze briefly its possible functions in ovulation-related diseases.We want to provide a reference in research areas of reproductive immunology. |
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Keywords: | TLRs mammals ovulation regulation biological functions |
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