动物毛发中β-受体激动剂残留消除规律及检测技术研究进展

畜禽养殖环节违法添加β-受体激动剂类药物,导致畜产品安全事件多发,我国政府对畜产品中β-受体激动剂监管高度重视。而动物毛发中β-受体激动剂残留消除缓慢,且毛发取样方便、无创伤、易于保存,作为监管β-受体激动剂在畜禽养殖环节违法添加的靶标具有很大优势。综述了毛发的结构特性与生长规律、药物进入毛发机制、动物毛发中β-受体激动剂残留消除规律及检测技术,旨在为毛发作为可能的监管靶标提供科学依据。

Advances on Residues and Detection of β-Agonists in Animal Hair

The illegal use of β-agonist in animal husbandry is very dangerous for animal products safety. Chinese government attaches great importance to β-agonists regulator of animal products. Most β-agonists eliminates slowly in animal hair. In addition, hair is non-invasive to take and easy to store. It has great advantage to use it as supervision target in animal husbandry. This review summarized the structure and growth pattern of hair, mechanism of how drug entering into hair, its residue elimination rule, and detection technology of β-agonists in animal hair. All these could provide scientific basis for taking animal hair as supervision target of β-agonists in animal husbandry.