Research Progress on Milk Protein Synthesis Regulated by Amino Acids in the Mammary Gland and Its Molecular Mechanism in Dairy Cows |
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Authors: | LI Ying XIANG Ai-li ZHENG Bai-qin ZHOU Xiao-qiao QIAO Jia-yun LIU Jing-xi WANG Wen-jie |
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Affiliation: | 1. Tangshan Animal Disease Prevention and Control Center, Tangshan 063000, China;2. Tangshan Animal Husbandry and Aquatic Products Quality Supervision center, Tangshan 063000, China;3. Institute of Animal Science and Veterinary, Tianjin Academy of Agricultural Sciences, Tianjin 300384, China |
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Abstract: | Milk proteins have great nutritional value,rich contain and balanced profile of amino acid,which provide nearly all the essential amino acids for the human body.However more than 90% of milk proteins are synthesed by the amino acids in the mammary gland.Furthermore,the amino acid is not only funcion as the substrates of milk protein synthesis,but also as the signaling molecules to regulate milk protein sysnthesis through mammalian target of rapamycin (mTOR) signaling pathways.It is essential to further study milk protein synthesis regulated by amino acids in the mammary gland and the molecular mechanism in dairy cows.The paper reviewed the supply of amino acids,metabolism of amino acids by mammary gland,factors affecting amino acid utilization and signal pathway for amino acid regulation in milk protein synthesis. |
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Keywords: | dairy cows milk protein amino acid signaling transduction pathway |
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