Research Progress on Function of Pig Bactericidal/Permeability-increasing Protein (BPI) and Its Application in Resistance Breeding |
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| Authors: | DAI Chao-hui DONG Wen-hua WU Jia-yun BAO Wen-bin WU Sheng-long |
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| Affiliation: | 1. Key Laboratory for Animal Genetics, Breeding, Reproduction and Molecular Design of Jiangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China;2. Jiangsu Engineering Research Center for the Reproduction and Healthy Breeding of Boar, Yangzhou 225009, China |
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| Abstract: | Bactericidal/permeability-increasing protein (BPI) has a strong effect on sterilization (mainly for G- bacteria),neutralizing the activity of lipopolysaccharide (LPS) and enhancing the phagocytosis of mononuclear cells and neutrophils to pathogenic bacteria.The biological functions of BPI have been researched widely in recent years,which is known as "super antibiotic" and has been explored by many scholars as a candidate gene for resistance.This author summarized the research progress and application prospect of the BPI gene in the pig resistant breeding by introducing the structure,biological function of BPI gene and its relationship with the resistance,which was aimed to provide theoretical references and basis for the function research of pig BPI gene and its practical application in resistance breeding in future. |
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| Keywords: | pig bactericidal/permeability-increasing protein disease resistant breeding |
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