| 适冷酶结构与功能的关系 |
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| 引用本文： | 陈秀兰,张玉忠. 适冷酶结构与功能的关系[J]. 中国农业科技导报, 2007, 9(3): 57-60 |
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| 作者姓名： | 陈秀兰 张玉忠 |
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| 作者单位： | 山东大学微生物技术国家重点实验室、山东大学海洋生物技术研究中心,济南250100 |
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| 基金项目： | 国家高技术研究发展计划(863计划);山东省自然科学基金;山东省优秀中青年科学家科研奖励基金 |
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| 摘 要： | 适冷酶是指在低温下具有较高的催化效率，对热相对不稳定的酶。近20年来，适冷酶得到广泛的研究。由于适冷酶结构和功能的特殊性，成为研究蛋白质结构和功能的好材料，其结构和功能的研究也越来越深入。对适冷酶的酶学、动力学和热力学特征，以及适冷酶结构与其活性、稳定性和柔性的关系进行了分析。
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| 关 键 词： | 适冷酶 结构 活性 柔性 稳定性 |
| 收稿时间： | 2007-04-29 |
| 修稿时间： | 2007-04-29 |
Relationship between Structure and Function in Cold-adapted Enzymes |
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| CHEN Xiu-lan,ZHANG Yu-zhong. Relationship between Structure and Function in Cold-adapted Enzymes[J]. Journal of Agricultural Science and Technology, 2007, 9(3): 57-60 |
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| Authors: | CHEN Xiu-lan ZHANG Yu-zhong |
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| Affiliation: | state Key Lab of Microbial Technology, Marine Biotechnology Research Center, Shandong University, Jinan 250100, China |
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| Abstract: | Cold-adapted enzymes are the enzymes which are thermolabile and have high catalytic efficiency at low temperatures. In the past 20 years, cold-adapted enzymes have been extensively studied. Because of the uniqueness of their structure and function, they become good materials to study protein structure and function. And studies on the structure and function of cold-adapted enzymes are becoming more and more detailed with time. In this review, characteristics of the enzymatics, dynatics and thermodynatics of cold-adapted enzymes, the relationship between their structure and activity and the relationship between their stability and flexibility were analyzed. |
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| Keywords: | cold-adapted enzymes structure activity flexibility stability |
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