| 丙烯酰胺神经毒性机制研究进展 |
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| 引用本文： | 宋亚鹏.丙烯酰胺神经毒性机制研究进展[J].畜牧兽医杂志,2010,29(2):43-45. |
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| 作者姓名： | 宋亚鹏 |
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| 作者单位： | 长治市畜牧兽医局,山西,长治,046000 |
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| 摘 要： | 一些高温烹饪的食品中含有丙烯酰胺(acylamide,AA)。AA主要侵害动物和人的神经系统,产生神经毒性,而引起神经系统病变。AA神经毒性的作用机制目前还不是很清楚,但目前研究主要集中在轴突退变、浦肯野细胞(Purkinie)损伤、离子作用、蛋白结合、细胞凋亡、氧化损伤等这几个方面。
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| 关 键 词： | 丙烯酰胺 神经毒性 机制 |
Advance in Mechanism of Acrylamide Neurotoxicity |
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| SONG Ya-peng.Advance in Mechanism of Acrylamide Neurotoxicity[J].Journal of Animal Science and Veterinary Medicine,2010,29(2):43-45. |
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| Authors: | SONG Ya-peng |
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| Institution: | SONG Ya-peng(Changzhi Animal Husb,ry , Veterinary Bereau,Changzhi Shanxi 046000,China) |
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| Abstract: | Some food cooked at high temperature contains acrylamide(AA).AA predominantly affects nervous system of animals and human and leads to neurotoxicity and nervous system lesions.The mechanism of action of AA neurotoxicity is not yet clear,however,current research focuses on axonal degeneration,Purkinje cell damage,ions action,protein binding,apoptosis and oxidative damage. |
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| Keywords: | acrylamide neurotoxiciy mechanism |
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