| 昆虫中肠Bt毒素受体氨肽酶N的研究进展 |
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| 引用本文： | 李赛男. 昆虫中肠Bt毒素受体氨肽酶N的研究进展[J]. 安徽农业科学, 2007, 35(9): 2523-2525. DOI: 10.3969/j.issn.0517-6611.2007.09.006 |
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| 作者姓名： | 李赛男 |
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| 作者单位： | 肇庆学院生物学系,广东肇庆,526061 |
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| 基金项目： | 广东省肇庆市科技项目(203301) |
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| 摘 要： | 氨肽酶N(APN)是昆虫中肠中主要的Bt毒素受体,它与Cry毒素特异结合后,毒素插入细胞膜,在膜上形成孔洞,细胞裂解,最终导致昆虫死亡.APN的变异导致昆虫对Bt敏感性下降甚至产生抗性.就APN的结构特征、分类、APN与Cry毒素的相互作用机制以及APN与昆虫Bt抗性的关系作一综述.
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| 关 键 词： | 苏云金芽孢杆菌杀虫晶体蛋白 氨肽酶N 受体 抗性 |
| 文章编号： | 0517-6611（2007）09-02523-03 |
| 收稿时间： | 2006-12-28 |
| 修稿时间： | 2006-12-28 |
Research Progress in the Insect Midgut Aminopeptidase N |
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| LI Sai-nan. Research Progress in the Insect Midgut Aminopeptidase N[J]. Journal of Anhui Agricultural Sciences, 2007, 35(9): 2523-2525. DOI: 10.3969/j.issn.0517-6611.2007.09.006 |
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| Authors: | LI Sai-nan |
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| Affiliation: | Biology Department, Zhaoqing University, Zhaoqing, Guangdong 526061 |
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| Abstract: | Aminopeptidase N is a major kind of receptors for Bt toxins in the midgut of insects.Cry toxins bind to APN on the midgut epithelium and a porein of the toxin inserts into the membrane forming a pore.The integrity of midgut epithelia cells is destroyed and the insect dies.The mutation of APN results in insects resistance to Bt toxins.With the development of the studies on APN,it is possible to find out some more efficient resistance management strategies.The research progress in the aminopeptidase N receptors on the midgut epithelial membrane of susceptible insects for Bacillus thuringiensis toxins was reviewed. |
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| Keywords: | Bacillus thuringiensis insecticidal crystal protein Aminopeptidase N Receptor Resistance |
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