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A field investigation of kennel cough: Efficacy of different treatments
Authors:M. V. Thrusfield  C. G. G. Aitken  R. H. Muirhead
Affiliation:Department of Veterinary Clinical Studies, University of Edinburgh, Royal (Dick) School of Veterinary Studies, Veterinary Field Station, Easter Bush, Roslin, Midlothian EH25 9RG;*Department of Statistics, University of Edinburgh, James Clerk Maxwell Building, The King's Buildings, Mayfield Road, Edinburgh EH9 3TZ
Abstract:The efficacy of antibiotics, corticosteroids and antitussives in the treatment of kennel cough was investigated in clinical cases in the field, using information recorded on questionnaires distributed to a random sample of veterinary practitioners in the United Kingdom. Analysis of the results demonstrated a statistically significant difference in the duration of coughing between treated and untreated dogs when a trimethoprim-sulphonamide combination, oxytetracycline, ampicillin/amoxycillin, or corticosteroid were administered alone, and when ampicillin/ amoxycillin-corticosteroid or trimethoprim-sulphonamide-corticosteroid combinations were given. The estimated median duration of coughing between treated and untreated animals when a trimethoprim-sulphonamide combination or ampicillin/amoxycillin were administered alone also differed significantly. The most efficacious drug was trimethoprim-sulphonamide, administered alone.
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