| 鸡新城疫活疫苗种毒HB1株和F株保存期试验 |
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| 引用本文： | 吴涛.鸡新城疫活疫苗种毒HB1株和F株保存期试验[J].中国兽药杂志,2011,45(6):13-15. |
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| 作者姓名： | 吴涛 |
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| 作者单位： | 中国兽医药品监察所,北京,100081 |
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| 摘 要： | 对不同保存年代的鸡新城疫活疫苗种毒HB1株（Ⅱ系）和F株（Ⅲ系）各3批进行了病毒含量测定和免疫原性试验。3批不同保存年代的鸡新城疫病毒HB1株和F株病毒含量均≥108.4EID50/0.1 mL,最小免疫量均≤2500 EID50。结果表明,鸡新城疫病毒HB1株和F株毒种在-70℃分别保存16年和19年,病毒含量和免疫原性仍符合《中华人民共和国兽用生物制品规程》（二〇〇〇年版）规定。
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| 关 键 词： | 鸡新城疫活疫苗种毒 保存期 病毒含量 免疫原性 |
| 收稿时间： | 4/9/2010 4:15:52 PM |
| 修稿时间： | 2010/11/29 0:00:00 |
Studies on Preservation Period of Master Seeds of Newcastle Disease Live Vaccines Strain Virus HB1 and F |
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| wutao.Studies on Preservation Period of Master Seeds of Newcastle Disease Live Vaccines Strain Virus HB1 and F[J].Chinese Journal of Veterinary Drug,2011,45(6):13-15. |
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| Authors: | wutao |
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| Institution: | China Institute of Veterinary Drug Control |
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| Abstract: | The virus titers and immunogenicity of three batches master seeds of live newcastle disease vaccine strains（HB1,class Ⅱ;F,class III） stored at temperature of-70℃ for different times were tested.The virus titers were all above 108.4EID50/0.1 mL and the immune minimum doses were all below 2500 EID50.The results showed that the virus content and immunogenicity of the master seeds of newcastle disease virus（HB1,class Ⅱ;F,class III） stored at temperature of-70℃ for 16 years or 19 years still conformed to the regulations of The People＇s Republic of China Veterinary Biological Products（2000 edition）. |
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| Keywords: | Master Seeds of Newcastle Disease Live Vaccine Preservation Period Virus titers Immunogenicity |
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