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COX-2 and sPLA2 inhibitory activity of aqueous extract and polyphenols of Rhizophora mangle (red mangrove) |
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| Authors: | Marrero Evangelina Sánchez Janet de Armas Elizabeth Escobar Arturo Melchor Gleiby Abad M J Bermejo Paulina Villar Angel M Megías J Alcaraz Maria J |
| Affiliation: | National Center for Animal and Plant Health, CENSA, Apdo 10, San José de las Lajas, La Habana, Cuba. evadidem@censa.edu.cu |
| Abstract: | The aqueous extract of Rhizophora mangle bark and its polyphenolic fractions showed remarkable in vitro antiinflammatory activity in a preliminary study. The low molecular weight fraction exhibited cyclooxygenase-2 inhibitory activity while the total aqueous extract and the low molecular weight fraction showed secretory phospholipase A(2) inhibitory activity. |
| Keywords: | Rhizophora mangle Antiinflammatory activity COX-2 inhibitory activity sPLA2 inhibitory activity |
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