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灰树花多糖对甲醛中毒小鼠淋巴细胞的干预作用
引用本文:张立霞,邵一叶,高永,崔大鹏,杨静,倪艳波.灰树花多糖对甲醛中毒小鼠淋巴细胞的干预作用[J].安徽农业科学,2010,38(3):1254-1255.
作者姓名:张立霞  邵一叶  高永  崔大鹏  杨静  倪艳波
作者单位:滨州医学院实验医学研究中心,山东烟台,264003;滨州医学院基础学院,山东烟台,264003;滨州医学院学报编辑部,山东烟台,264003
摘    要:目的]观察灰树花多糖对甲醛中毒小鼠淋巴细胞的干预作用。方法]取3周龄小鼠,腹腔注射生理盐水和不同浓度的灰树花多糖,10d后制作甲醛中毒模型,正常对照组不作任何处理。利用淋巴细胞计数测定淋巴细胞的数目,利用流式细胞仪检测淋巴细胞的凋亡。结果]生理盐水组小鼠淋巴细胞数目降低,淋巴细胞凋亡率升高,中、高剂量灰树花多糖组淋巴细胞的损伤明显减轻,与生理盐水组的差异有统计学意义(P〈0.01)。结论]灰树花多糖对甲醛中毒小鼠淋巴细胞有保护作用。

关 键 词:灰树花多糖  甲醛  淋巴细胞  凋亡

The Intervention Effects of Grifola Frondosa Polysaccharide on Lymphocytes in Mice Exposured to Formaldehyde
ZHANG Li-xia et al.The Intervention Effects of Grifola Frondosa Polysaccharide on Lymphocytes in Mice Exposured to Formaldehyde[J].Journal of Anhui Agricultural Sciences,2010,38(3):1254-1255.
Authors:ZHANG Li-xia
Institution:Experimental Medicine Research Center of Binzhou Medical College;Yantai;Shandong 264003
Abstract:Objective] The paper aimed to observe the intervention effect of Grifola frondosa polysaccharide on lymphocytes in mice exposured to formaldehyde.Method] 3-week-old mice was exposed to formaldehyde after intraperitoneal injecting of saline and different concentrations of Grifola frondosa polysaccharide 10 days while the control group without any treatment.The number of lymphocytes was determined by Cell count board.The rate of lymphocytes apoptosis were determined by flow cytometry.Result] The number of ...
Keywords:Grifola frondosa polysaccharide  Formaldehyde  Lymphocytes  Apoptosis  
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