辽宁庄河奶山羊“腰麻痹病”病原学及病理形态学研究

5例自然感染“腰麻痹病”奶山羊的病灶均局限在脑脊髓系统,其中1例脊髓腔中发现1条活泼的指状腹腔丝虫幼虫,在另一例脊髓实质病变部发现了与指状腹腔丝虫断面相似的虫体断面.各例病变性质均属虫伤性液化坏死性非化脓性脑脊髓炎变化.由此认为,指状腹腔丝虫幼虫是本病的病原.病灶的超微结构观察表明,病变无特异性,主要呈退行性病理变化:神经元、神经胶质细胞及细胞器呈严重的细胞病变,有髓神经纤维脱髓鞘,无髓神经纤维变性溶解,神经毡形成坏死性空洞及出血等变化.

The Study of Aetiology and Pathomorphology of Milch Goats With "Lumbar Paralysis" in Zhuanghe of Liaoning Province

The lesions of five milch goats naturally suffered from "lumbar paralysis" were all confined to the cerebrospinal system. There was an active larva of Setaria digitata in spinal cavity in one case and a worm section similar to that of larva of Setaria digitata was found in the spinal parenchyma of other affected goat. All the lesions observed were generally the characteristies of insect-biting, liquefacient-necrotic and apyogenous encephalomyelitis. Besides, the ultra-structural observation indicated that the lesions are non-specific and are mainly characterized by the retrograde pathological changes, such as the serious cellular alterations of neurons, neuroglio-cytes and organelles, demyelination of medullated fiibers, degenerative dissolution of nonmedul-lated fibers and necrotic caverns and hemorrhages on neuropil, etc. It is thus believed that this disorder is caused by the infestation of the larva of Setaria digitata.