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肝硬化并自发性细菌性腹膜炎患者血清和腹水一氧化氮的测定及临床意义
引用本文:黄兴国,庄桂龙,詹雨林.肝硬化并自发性细菌性腹膜炎患者血清和腹水一氧化氮的测定及临床意义[J].湛江医学院学报,2003,21(5):449-450.
作者姓名:黄兴国  庄桂龙  詹雨林
作者单位:广东省深圳市龙岗中心医院 广东深圳518116 (黄兴国,庄桂龙),广东省深圳市龙岗中心医院 广东深圳518116(詹雨林)
摘    要:目的 :观察肝硬化并自发性细菌性腹膜炎 (SBP)患者血清和腹水中一氧化氮 (NO)水平的变化及临床意义。方法 :肝硬化腹水 72例分为SBP组 (n =4 0例 )和漏出液组 (n =32例 ) ,采用Gress法测定两组患者血清和腹水的NO的变化。结果 :SBP组血清和腹水的NO水平明显高于漏出液组 (P <0 .0 1 ) ;SBP组腹水NO水平又明显高于血清中的NO水平 ,且随着感染的控制 ,腹水中NO水平明显下降 (P <0 .0 1 )。结论 :腹水NO的检测有助于SBP的诊断和疗效观察

关 键 词:肝硬化  自发性腹膜炎  腹水  一氧化氮(N0)
文章编号:1005-4057(2003)05-0449-02
修稿时间:2003年2月4日

Serum and ascitic fluid nitric o xide levels in patients with cirrhosis and spontaneous bacterial peritonitis
HUANG Xing guo,ZHUANG Gui long,ZHAN Yu lin.Serum and ascitic fluid nitric o xide levels in patients with cirrhosis and spontaneous bacterial peritonitis[J].Journal of Guangdong Medical College,2003,21(5):449-450.
Authors:HUANG Xing guo  ZHUANG Gui long  ZHAN Yu lin
Abstract:Objective:To study the clinical significance of serum and ascitic fluid nitric oxide (NO) levels in patients with cirrhosis and spontaneous bacterial peritonitis(SBP).Methods:NO contents were detected by Gress method in 40 cirrhotic patients with SBP and 32 cirrhotic patients without SBP.Results:Serum and ascitic fluid NO levels were high in patients with SBP as compared with those without SBP( P <0.01).In SBP patients,NO levels from ascitic fluid were superior to those from serum,and there was an obvious decrease of ascitic fluid NO levels with the control of infection ( P <0.01).Conclusion:Detection of NO levels from ascitic fluid is helpful to diagnosing SBP and evaluating the efficacy.
Keywords:cirrhosis  spontaneous bacterial peritonitis  ascitic fluid  nitric oxide
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