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Cyclic adenosine 3',5'-monophosphate during glucose repression in the rat liver
Authors:O Sudilovsky  A Pestana  P H Hinderaker  H C Pitot
Abstract:Intragastric administration of glucose inhibits the induction of serine dehydratase and tyrosine aminotransferase by glucagon in rat liver, but has no effect on the increase in hepatic adenosine 3',5'-monophosphate resulting from administration of glucagon. Thus, glucose repression in mammalian liver, unlike catabolite repression in microorganisms, appears to operate independently of the amounts of cyclic nucleotide in the cells.
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