| 猪丹毒杆菌C43005株的制备及检定 |
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| 引用本文： | 王秀丽. 猪丹毒杆菌C43005株的制备及检定[J]. 中国兽药杂志, 2017, 51(3): 21-26 |
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| 作者姓名： | 王秀丽 |
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| 作者单位： | 中国兽医药品监察所 北京 100081 |
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| 摘 要： | 为研究猪丹毒杆菌C43005株的菌种特性,制备了一批猪丹毒杆菌C43005株并对菌种的真空度、剩余水分、形态、培养特性、生化特性、血清学特性、毒力、免疫原性等参数进行检定,重点对该菌种的毒力进行重复试验并对影响毒力的因素进行分析。结果表明,菌种的真空度、剩余水分、形态、培养特性、生化特性、血清学特性、免疫原性均符合《中华人民共和国兽用生物制品规程》二〇〇〇版相关质量标准的规定,毒力试验结果明显受培养基质量和动物个体差异的影响。本研究可以为猪丹毒杆菌C43005株的制备和检定提供参考依据。
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| 关 键 词： | 猪丹毒杆菌C43005，毒力，免疫原性 |
| 收稿时间： | 2016-11-09 |
| 修稿时间： | 2017-01-23 |
The Preparation and Verification of Swine Erysipelas Bacillus C43005 strain |
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| Affiliation: | China Institute of Veterinary Drug Control Beijing 100081 |
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| Abstract: | A batch of swine erysipelas bacillus C43005 strain was prepared and the vacuum degree, residual moisture, morphology, culture characteristics, biochemical properties, serological characteristics, virulence, immunogenicity were tested, which can provide some reference data to the preparation of swine erysipelas bacillus C43005 strain. The virulence experiment of C43005 was repeated and the influence factors were analyzed. The results showed that the vacuum degree, residual moisture, morphology, culture characteristics, biochemical properties, serological characteristics, immunogenicity conformed to the law of People''s Republic of China Veterinary Biological Products Regulation(2000 version), and the virulence test results were obviously affected by medium quality an individual differences of experimental animals. |
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