Heterologous helminth induced resistance to Ascaris suum in guinea pigs |
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Authors: | Bert E Stromberg EJL Soulsby |
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Institution: | Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pa. 19174 U.S.A. |
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Abstract: | The protection inducing capacity of Toxocara canis, Ancylostoma caninum, Haemonchus contortus, Caenorhabditis briggsae and Turbatrix aceti given via the mesenteric vein to a challenge infection with Ascaris suum was evaluated. Embryonated eggs and second stage larvae of T. canis and infective larvae of A. caninum were able to induce a statistically significant level of protective immunity, while the other non-related helminths were unable to protect against a challenge infection. |
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