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肠宁(CN)的急性及蓄积毒性试验研究
引用本文:冯旭,鞠玉林,王楠.肠宁(CN)的急性及蓄积毒性试验研究[J].吉林畜牧兽医,2004(7):31-32.
作者姓名:冯旭  鞠玉林  王楠
作者单位:延边大学农学院动物医学系,吉林,龙井,133400;延边大学农学院动物医学系,吉林,龙井,133400;延边大学农学院动物医学系,吉林,龙井,133400
摘    要:为了提供中药肠宁(CN)的安全毒理学评价资料,本试验采用改良Karber法测定小白鼠的 LD50>60 973 mg/kg;在蓄积毒性试验中,小白鼠未表现出蓄积毒性。这说明中药肠宁属于实际无毒 性物质,并无蓄积毒性作用。

关 键 词:肠宁  小白鼠  毒性试验

Studies on the Toxicity Test of CN
FENG Xu,JU Yu-lin,WANG Nan.Studies on the Toxicity Test of CN[J].Jilin Animal Science and Veterinary Medicine,2004(7):31-32.
Authors:FENG Xu  JU Yu-lin  WANG Nan
Abstract:To improve safety toxicology evaluation material of CN, The test of LD50 was examined by the better Barber means; The accumulative toxicity test was studied by the twenty-day accumulative test in mice .The results demonstrated that LD50 was over 60 973mg/kg in the acute toxicity test; there was not obvious accumulatively in mice in the accumulative toxicity test .The results suggested that CN was Impoisonous material.
Keywords:CN  Mice  Toxicity test
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