| 猪丹毒QL251弱毒菌株的稳定性试验 |
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| 引用本文： | 罗玉峰,钱心元.猪丹毒QL251弱毒菌株的稳定性试验[J].中国兽药杂志,1997,31(1):19-21. |
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| 作者姓名： | 罗玉峰 钱心元 |
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| 作者单位： | 中国兽药监察所 |
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| 摘 要： | 猪丹毒ＱＬ２５１弱毒株在马丁肉汤、血液琼脂斜面、小白鼠及猪丹毒敏感猪体内连续传代后，测其安全性和免疫原性。试验证明，ＱＬ２５１无论是在培养基上，还是在动物体内传代后都是稳定的，仍然保持了原有的特性。
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| 关 键 词： | 猪丹毒 弱毒菌株 稳定性试验 |
On the Stability of Attenuated Erysipelothrix rhusiopathiae QL251 |
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| Luo Yufeng,Qian Xinyuan,Fang Yanli The National Control Institute of Veterinary Bioproducts and Pharmaceuticals,Beijing.On the Stability of Attenuated Erysipelothrix rhusiopathiae QL251[J].Chinese Journal of Veterinary Drug,1997,31(1):19-21. |
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| Authors: | Luo Yufeng Qian Xinyuan Fang Yanli The National Control Institute of Veterinary Bioproducts and Pharmaceuticals Beijing |
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| Institution: | Luo Yufeng,Qian Xinyuan,Fang Yanli The National Control Institute of Veterinary Bioproducts and Pharmaceuticals,Beijing 100081 |
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| Abstract: | For the purpose of demonstration of the stability of the Erysipelothrix rhusiopathiae QL251 as an attenuated vaccine strain.This strain was either serially cultured in vitro in Martin broth for 50 passages and blood agar for 55 passages respectively or passed in vivo inmice for 27 passages and in pigs for 5 passages respectively.No change both in immunogenicity and in safteness for animals were observed. The auther suggast that this strain QL251 is satisfactory for the production of live swine erysipelas vaccine. |
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| Keywords: | Erysipelothrix rhusiopathiae attenuated vaccine strain stability |
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