The efficacy of mebendazole and praziquantel againstTaenia saginata cysticercosis in cattle

Approximately 50,000Taenia saginata eggs were given orally to bullocks. Ten weeks later, mebendazole or praziquantel was administered in the fodder in single or multiple doses. The animals were slaughtered at intervals after medication when the numbers and viability of cysticerci in various sites were recorded. Single doses of 5 mg/kg mebendazole or 10 mg/kg praziquantel had little effect on the viability of cysticerci. One single dose of 25 mg/kg or 10 daily doses of 5 mg/kg mebendazole had some effect. Praziquantel was completely effective against the viability of cysticerci in either one single dose of 100 mg/kg or 10 daily doses of 10 mg/kg.