| 重度联合免疫缺陷（SCID）小鼠性机能发育的初步研究 |
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| 引用本文： | 周虚 孙敬方. 重度联合免疫缺陷（SCID）小鼠性机能发育的初步研究[J]. 黑龙江动物繁殖, 1999, 7(4): 3-4 |
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| 作者姓名： | 周虚 孙敬方 |
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| 作者单位： | 中国人民解放军军需大学动物科技系!长春130062(周虚)，南京军区总医院医学动物实验中心(孙敬方，田小芸) |
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| 基金项目： | 军队医药卫生科研基金!96M115 |
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| 摘 要： | 本研究对ＳＣＩＤ小鼠与ＢＡＬＢ／ｃ小鼠的阴道开口时间，卵泡发育，精子发生及血浆促黄体素（ＬＨ）和睾酮（Ｔ）浓度进行了比较观察，结果表明，２种鼠阴道开口时间均为４０日龄，均在３０日龄时卵巢出现有腔卵泡，但ＳＣＩＤ雌鼠４５日龄有排卵，而同龄ＢＡＬＢ／ｃ雌鼠未见排卵；ＳＣＩＤ雄鼠４０日龄附睾涂片有活精子，ＢＡＬＢ／ｃ雄鼠４５日龄附睾涂片可见活精子，ＳＣＩＤ小鼠初情期似乎有比ＢＡＬＢ／ｃ小鼠初情期略早的趋
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| 关 键 词： | 小鼠 卵鼠 睾丸 SCID 初情期 BALB／C 发育 |
A Preliminary Study on Development of Sexual Function in SCID Mouse |
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| Zhou Xu,Sun Jingfang,Tian Xiaoyun. A Preliminary Study on Development of Sexual Function in SCID Mouse[J]. Heilongjiang journal of animal reproduction, 1999, 7(4): 3-4 |
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| Authors: | Zhou Xu Sun Jingfang Tian Xiaoyun |
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| Abstract: | We have made a comparison between SCID and BALB/c mouse in the time of virgina open. follicular development, spermatogenesis. and plasma levels of luteinizing hormone (LH) and testosterone (T) during and after sexual maturation. The results showed that the time of virgina open was 40 days of age and the first antral follicles appeared at 30 days of age in both of SCID and BALB/c mouse, However, SCID mouse ovulated during 40-45 days of age. In males. active spermatozoa were first seen in the slides from epididymas of 40-day-old SCID mouse and 45-day -old BALB/c mouse. It seemed that SCID mouse tends to reach puberty a little bit earlier than BALB/c mouse. The plasma levels of LH and T were not different between SCID and BALB/c mouse, both before and after sexual maturation. |
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| Keywords: | SCID mouse sexual maturation Ovulation Spermatogenesis LH P |
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