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USE OF 123IODINE METAIODOBENZYLGUANIDINE SCINTIGRAPHY FOR THE DIAGNOSIS OF A PHEOCHROMOCYTOMA IN A DOG
Authors:Clifford R  Berry  DVM  Kathy N  Wright  DVM  Edward B  Breitschwerdt  DVM  Jerome M  Feldman  MD
Institution:Departments of Anatomy, Physiological Sciences, and Radiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC;Departments of Companion Animal and Special Species, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606;Department of Medicine, Duke University Medical Center, Durham, NC 27710.
Abstract:A 13-year-old neutered female Yorkshire terrier presented with a history of progressive episodic weakness and disorientation of 4 months duration. Physical and neurologic examinations were normal at presentation. Abdominal ultrasound revealed a mass involving the right adrenal gland. Standard planar scintigraphy was performed at 4, 18, and 24 hours after intravenous injection 185 MBq (5mCi) of 123I-labeled metaiodobenzylguanidine (123I-MIBG). An area of focal intense uptake was identified in the area of the right adrenal gland. A pheochromocytoma was confirmed histologically after surgical excision.
Keywords:canine pheochromocytoma              123I-MIBG scintigraphy
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