Endogenous Anticoagulants |
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Authors: | Amy Kubier Mauria O'Brien |
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Institution: | University of Illinois Urbana-Champaign, Champaign, IL, USA |
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Abstract: | Blood coagulation is a complex and highly coordinated process that is constantly altered and impacted by procoagulant and anticoagulant “players.” It is vital that these components work in concert to maintain a balance to keep coagulation in check. Several important endogenous anticoagulants will be discussed in this review including tissue factor pathway inhibitor, antithrombin, protein C, and protein S in origin, structure, mechanism of action, effects of deficiency, and current knowledge in veterinary medicine. |
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