Basal and ACTH-Stimulated Plasma Aldosterone Concentrations are Normal or Increased in Dogs With Trichuriasis-Associated Pseudohypoadrenocorticism |
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| Authors: | Thomas K Graves William D Schall Kent Refsal Raymond F Nachreiner |
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| Institution: | Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Ml;Animal Health Diagnostic Laboratory, Michigan State University, East Lansing, Ml |
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| Abstract: | We measured plasma concentrations of Cortisol and aldosterone before and after administration of adrenocorticotropin (ACTH) in dogs with trichuriasis. These dogs had physical examination, historical, and serum electrolyte findings suggestive of hypoadrenocorticism; trichuriasisassociated pseudohypoadrenocorticism has been reported previously. We found normal basal and ACTH-stimulated plasma Cortisol concentrations. Basal and ACTH-stimulated plasma aldosterone concentrations were normal in 2 dogs and increased in 3 dogs, suggesting that the electrolyte abnormalities seen in this clinical syndrome are not due to aldosterone deficiency. |
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