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孕兔细胞免疫功能状态的探讨外周血淋巴细胞ANAE阳性率观察
引用本文:陈秀鹤,幸志光,李宪智,卢军,冯志梅.孕兔细胞免疫功能状态的探讨外周血淋巴细胞ANAE阳性率观察[J].河北农业大学学报,1989(3).
作者姓名:陈秀鹤  幸志光  李宪智  卢军  冯志梅
作者单位:河北农业大学畜牧兽医系,河北农业大学畜牧兽医系,河北农业大学畜牧兽医系,河北农业大学畜牧兽医系,河北农业大学畜牧兽医系
摘    要:孕体是半非自己的同种异体移植物,妊娠时,母体对胎儿为什么不产生排斥?我们采用了酸性 a—醋酸酯酶(ANAE)反应标记淋巴细胞的细胞化学方法,观察了32例正常孕兔,并分早、中、晚三期和33例正常未孕成年兔作对照,对孕兔细脆免疫功能状态进行了探讨。结果表明:妊娠各期淋巴细胞百分率与未孕组差异不显著(P>0.05);妊娠各期淋巴细胞 ANAE 阳性率均下降,与未孕组有极显著性差异(P<0.01),临产期又有回升,与妊娠中期差异极显著(P<0.01)。此结果支持了妊娠期细脆免疫功能降低的学说。

关 键 词:家兔  细胞免疫

A Survey of State of Rabbits Cell-mediated Immunity Function During Pregnancy:observation of ANAE(+)Lymphocytes in Peripheral Blood
Chen Xiuhe Xing Zhiguang Li Xianzhi Lu jun Feng Zhimei.A Survey of State of Rabbits Cell-mediated Immunity Function During Pregnancy:observation of ANAE(+)Lymphocytes in Peripheral Blood[J].Journal of Agricultural University of Hebei,1989(3).
Authors:Chen Xiuhe Xing Zhiguang Li Xianzhi Lu jun Feng Zhimei
Abstract:Using cytochemical Acid L-Naphthay Acetate Esterase(ANAE)reac- tion method to mark lymphocytes,compare numeral change of ANAE(+) lymphocytes of 32 rabbits in early,middle and later different pregnant pe- riod with 33 nonpregnant rabbits.It showed that the percentage of ANAE(+)lymphocytes in the different pregnant rabbits was lower than nonpregnancy. The difference of two groups was statistically significant. The results support the hypothesis that the function of cell-mediated immunity is decreased during pregnancy.
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