| 重大禽病浓缩疫苗的研制 |
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| 引用本文： | 何叶峰,徐怀英,欧阳文军,秦卓明.重大禽病浓缩疫苗的研制[J].水禽世界,2003(12):8-11. |
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| 作者姓名： | 何叶峰 徐怀英 欧阳文军 秦卓明 |
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| 作者单位： | 山东省农业科学院家禽研究所SPF鸡研究中心,济南,250100 |
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| 摘 要： | 利用PALL滤器将灭活后的新城疫、禽流感、传染性支气管炎、产蛋下降综合征等病毒分别进行10倍浓缩,经检验合格后,分别按照一定比例将抗原浓缩液与灭菌的医用白油配比,经胶体磨制备成三联或四联油乳剂灭活疫苗,均通过了实验室的各项指标检测。经过在隔离器进行实验室安全和效力检验,以及田间试验证明,该疫苗安全有效,抗体水平高,维持时间长,能够保护鸡群抵抗新城疫、禽流感、传染性支气管炎等强毒的攻击。
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| 关 键 词： | 浓缩疫苗 安全试验 效力检验 |
| 文章编号： | 1006-9755(2003)12-0008-04 |
| 修稿时间： | 2003年9月28日 |
Research of Concentrated Vaccine against Important Poultry Disease |
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| HE Ye-feng,XU huai-ying,OU YANG Wen-jun,QIN Zhuo-ming.Research of Concentrated Vaccine against Important Poultry Disease[J].Poultry Science,2003(12):8-11. |
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| Authors: | HE Ye-feng XU huai-ying OU YANG Wen-jun QIN Zhuo-ming |
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| Abstract: | Inactivated Newcastle disease virus(NDV),avian influenza virus(AIV) ,infectibronchitis virus(IBV)and egg drop syndrome virus(EDSV)was concentrated 1 0 times by PALL colander.Then the concentrated antigen was mixed with mieral oil according to certain proportion and made into inactivate oil vaccine.Safety and efficacy tests were carried out,the results showed that the vaccine was safe an d efficacious,and could protected the chickens from the challenge of NDV,AIV,IBV and EDSV. |
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| Keywords: | concentrated vaccine safety tests efficacy tests |
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