Interdigital involvement in a case of primary cutaneous canine histoplasmosis in Japan |
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Authors: | Nishifuji K Ueda Y Sano A Kadoya M Kamei K Sekiguchi M Nishimura K Iwasaki T |
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Affiliation: | Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo160-8582. |
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Abstract: | A 5-year-old male Siberian husky bred outdoor in Tokyo had a swollen paw with interdigital granulomatous lesions in the left hindlimb. The dog had no apparent pulmonary or gastrointestinal involvement. Histopathological analysis of the skin lesions demonstrated yeast-like organisms predominantly within macrophages. Sequence analysis of fungal ribosome RNA gene isolated from a paraffin sample revealed a 100% homology with the teleomorph of Histoplasma capsulatum. The present case may support the concept of primary cutaneous canine histoplasmosis as an endemic phenotype recognized in Japan. |
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