全国设施蔬菜生产可持续发展学术研讨会在沈阳召开

会议由中国园艺学会主办 ,中国农业工程学会设施园艺工程专业委员会协办 ,沈阳农业大学园艺系承办 ,于 2 0 0 0年 4月 19日至 2 2日在沈阳农业大学召开。来自我国 13个省、自治区、直辖市的与会代表共 78人 ,会议论文 4 3篇 ,由沈阳农业大学学报专刊发表。经承办单位和与会者努力 ,会议圆满成功。开幕式由中国园艺学会副理事长李树德研究员主持 ,辽宁省科技厅、农业厅、沈阳市副食品局、沈阳农业大学的领导到会祝贺并发表讲话。会议就确定的主题进行了大会发言 ,小组讨论及现场考察。代表们欣喜地看到 ,近 2 0年来我国蔬菜设施生产迅猛发展 …

The effect of phospholipase A2 inhibitor DTNB on the rat ischemia reperfusion arrhythmia

AIM: To determine the effects of phospholipase A₂ (PLA₂) and K_ATP on rat ischemia/reperfusion(I/R)-induced arrhythmia. METHODS: Myocardial ischemia and reperfusion were produced by occlusion and reirregation of the left anterior descending artery(LAD). An inhibitor of PLA₂, 5,5'-dithio-bis(2-nitrobenzoic acid) (DTNB) (16 mg /kg), a K_ATP opener pinacidil (0.2 mg/kg), a K_ATP blocker glibenclamide (0.3 mg/kg) was used 5 min prior to 10 min regional ischemia and 10 min reperfusion. RESULTS: DTNB (16 mg/kg) reduced the scores of arrhythmia, creatine kinase (CPK) and lactate dehydrogenase(LDH) (P＜0.05). Glibenclamide had no effect on I/R arrhythmia, but increased CPK and LDH (P＜0.05). After K_ATP was blocked by glibenclamide, DTNB led to lethal ventricular fibrillation and increase LDH, higher than without DTNB (P＜0.05). Pinacidil depleted ventricular fibrillation and ventricular tachycardia. CONCLUSIONS: PLA₂ inhibitor DTNB enhances membrane stability both in structure and function, so that reduces myocardial damage caused by I/R, and suggests that PLA₂ plays an important role on myocardial I/R arrhythmia, and also implies that activated K₊ATP prevents rats from I/R arrhythmia under condition of our experiments, but the relationship between DTNB protective effect and K_ATP activity remains indefinite.