Five new amicoumacins isolated from a marine-derived bacterium Bacillus subtilis |
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| Authors: | Li Yongxin Xu Ying Liu Lingli Han Zhuang Lai Pok Yui Guo Xiangrong Zhang Xixiang Lin Wenhan Qian Pei-Yuan |
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| Affiliation: | KAUST Global Collaborative Research, Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China. liyongxin@ust.hk |
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| Abstract: | Four novel amicoumacins, namely lipoamicoumacins A-D (1-4), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR, CD and MS) analysis and in comparison with data in literature. |
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| Keywords: | antibacterial cytotoxicity lipoamicoumacin Bacillus subtilis |
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