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New cytotoxic cembranolides from the soft coral Lobophytum michaelae
Authors:Wang Shang-Kwei  Duh Chang-Yih
Institution:Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan. skwang@cc.kmu.edu.tw
Abstract:Six new cembranolides, michaolides L–Q (1–6), and a known cembranolide, lobomichaolide (7) were isolated from the CH2Cl2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 1–7 and their cytotoxicity against selected cell lines were evaluated.
Keywords:Lobophytum michaelae  cembranolides  cytotoxicity
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