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Neuronal vacuolation in an adult ferret
Authors:Hamir Amir N  Miller Janice M  Yaeger Michael J
Institution:National Animal Disease Center, ARS, USDA, 2300 Dayton Road, P.O. Box 70, Ames, Iowa 50010, USA. ahamir@nadc.ars.usda.gov
Abstract:The brain of a ferret showing abnormal neurologic signs was evaluated by histopathologic, histochemical, immunohistochemical, and ultrastructural examinations. Extensive neuronal vacuolation was observed. Since the brain was negative for protease-resistant protein prion (PrP'"), it was concluded that this was not a case of transmissible spongiform encephalopathy.
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