玉米须总黄酮提取工艺及其降血糖作用研究

目的]研究玉米须总黄酮提取工艺及降血糖作用。方法]以玉米须为材料,通过正交设计考察乙醇浓度、料液比、提取时间对玉米须总黄酮提取率的影响,确定最佳工艺条件;并以四氧嘧啶所致糖尿病小鼠为动物模型,研究玉米须提取物的降血糖作用。结果]玉米须总黄酮提取最佳条件为16倍70%乙醇,回流2次,每次浸提2 h。动物试验表明,玉米须提取物高剂量组能显著抑制四氧嘧啶所致糖尿病小鼠模型血糖的持续升高(P0.05)。结论]玉米须提取物具有辅助降血糖作用。

Study on Extraction Technology of Total Flavonoids from Corn Silk and Its Hypoglycemic Effect

Objective] The research aimed to study extraction technology of total flavonoids from corn silk and its hypoglycemic effect.Method]With corn silk as material,the effects of different ethanol concentration,ratio of solid to liquid,extraction time and extraction times were taken to optimize extraction technology of total flavonoids from corn silk by orthogonal design.Also,the hypoglycemic effect of the alcohol extract of corn milk was studied in diabetic model rats induced by alloxan.Result]The best extract technology was to distill with 16 times 70% ethanol,refluxed 2 times and extracted for 2 h.Also,the high dosage group of the extract had the significantly inhibition on rising the blood glucose of diabetic model rats induced by alloxan(P<0.05).Conclusion]The extract of corn silk has the auxiliary hypoglycemic effect.