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乳酸杆菌与肠道黏附相关表面因子及其机制的研究进展
引用本文:汪海峰,章文明,汪以真,刘建新. 乳酸杆菌与肠道黏附相关表面因子及其机制的研究进展[J]. 动物营养学报, 2011, 23(2): 179-186. DOI: 10.3969/j.issn.1006-267x.2011.02.001
作者姓名:汪海峰  章文明  汪以真  刘建新
作者单位:汪海峰,WANG Haifeng(浙江农林大学林业与生物技术学院动物科学系,临安,311300;浙江大学动物科学学院,杭州,310029);章文明,汪以真,刘建新,ZHANG Wenming,WANG Yizhen,LIU Jianxin(浙江大学动物科学学院,杭州,310029)
基金项目:国家自然科学基金,中国博士后科学基金,浙江省自然科学基金,浙江省农业重大科技专项重点项目
摘    要:乳酸杆菌为应用最早、研究最多的益生菌种之一.乳酸杆菌通过表面分子对肠道形成黏附和定植而发挥生理作用,包括养分消化吸收、排斥病原菌和调节免疫等.本文就乳酸杆菌表面蛋白(S层蛋白、引物酶sortase依赖蛋白、黏膜结合蛋白和胞外间质黏附的调节性表面蛋白)和非蛋白类黏附相关因子(脂磷壁酸和细胞外多糖)结构及其在黏附中作用的研...

关 键 词:乳酸杆菌  表面蛋白  磷壁酸  细胞外多糖  黏附

Cell Surface Components of Lactobacilli:Recent Advances on Their Adherence Mechanism of Action in the Gastrointestinal Tract
WANG Haifeng,ZHANG Wenming,WANG Yizhen,LIU Jianxin. Cell Surface Components of Lactobacilli:Recent Advances on Their Adherence Mechanism of Action in the Gastrointestinal Tract[J]. CHINESE JOURNAL OF ANIMAL NUTRITION, 2011, 23(2): 179-186. DOI: 10.3969/j.issn.1006-267x.2011.02.001
Authors:WANG Haifeng  ZHANG Wenming  WANG Yizhen  LIU Jianxin
Affiliation:WANG Haifeng1,2 ZHANG Wenming2 WANG Yizhen2 LIU Jianxin2 (1.Department of Animal Science,College of Forestry and Biotechnology,Zhejiang A & F University,Lin'an 311300,China,2.College of Animal Science,Zhejiang University,Hangzhou 310029,China)
Abstract:Lactobacilli,identified as one of the most common members of intestinal microbiota,have been applied and studied considerably.They are often considered as probiotics for animal or human.The Lactobacilli play an important physiological role in the host through adherence and colonization in the intestinal tract,including digestion and absorption of nutrients,protection against pathogen colonization and immune modulation.This article has reviewed the cell surface architecture and adherence mechanism of Lactoba...
Keywords:Lactobacilli  surface layer protein  teichoic acids  exopolysaccharides  adherence  
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