| 肠内细菌对天然药物的化学修饰 |
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| 引用本文： | 赵锐,邢增涛.肠内细菌对天然药物的化学修饰[J].吉林农业大学学报,1998,20(2):103-110. |
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| 作者姓名： | 赵锐 邢增涛 |
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| 作者单位： | 吉林农业大学中药材学院 |
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| 摘 要： | 概述了目前国前国内外利用肠内细菌对天然药物进行生物化学修饰的研究进展情况，其中包括利用大鼠，豚鼠，家兔等试验动物及其肠内细菌对懈皮素和其糖苷－芦丁（＋）－儿茶素（４－＾１４Ｃ）－鹰嘴豆芽素Ａ１伞形花内酯和脱肠草素，芹菜素（５，７，４－三羟基黄酮）苦杏仁苷，人对皂甙Ｒｇ１及Ｒｂ１和厚朴酚，厚朴酚等的代谢，也包括利用人体肠内细菌对潘泻叶苷，异草素，当药苦苷，龙胆苦苷，桃叶珊瑚苷，京尼平苷，桅子苷，芍药
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| 关 键 词： | 肠内细菌 代谢 化学修饰 天然药物 |
Chemical Modification of Natural Drug by Intestine Bacteria |
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| Zhao Rui et al..Chemical Modification of Natural Drug by Intestine Bacteria[J].Journal of Jilin Agricultural University,1998,20(2):103-110. |
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| Authors: | Zhao Rui |
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| Abstract: | This paper reported that the research progress of chemical modification of natural organic compound by intestine bacteria. The contents are as follow: quercetin and its glycostine rutin, ( ) catechin, 4 14 C sparteine A, umbelliprenin, apigenin, amygdalin, ginsenoside Rg 1, and honokiol and magnolol were metabolized by rat, guinea pig, rabbits and so on; and folium sennoside, swertiamarin, gentiopicroside, aucubin, geniposide, paeoniflorin, albiflorin were metobolized by human intestine bacteria. |
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| Keywords: | intestine bacteria metobolizm chemical modification |
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