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Avian Paramyxoviridae--recent developments
Authors:D J Alexander
Institution:Central Veterinary Laboratory, New Haw, Weybridge, Surrey, Great Britain.
Abstract:This paper reviews the recent developments related to members of the Paramyxoviridae family which infect avian species. These developments include: (1) The identification of the virus responsible for the diseases turkey rhinotracheitis and swollen head syndrome in chickens as a member of the Pneumovirus genus, the first of this type to be isolated from birds. (2) The use of monoclonal antibodies prepared against Newcastle disease virus (NDV) and other avian paramyxoviruses which has enabled more exact and rapid diagnosis and greater understanding of the epizootiology of these viruses. (3) The nucleotide sequencing of the genome of NDV and subsequent amino acid sequencing of the major virus proteins have resulted in greater understanding of the pathogenicity of this economically important virus.
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