| 小牛胸腺免疫抑制提取物对体外培养细胞生长的影响 |
| |
| 引用本文： | 朱少璇 王豫生. 小牛胸腺免疫抑制提取物对体外培养细胞生长的影响[J]. 湛江医学院学报, 1997, 15(4): 331-332,335 |
| |
| 作者姓名： | 朱少璇 王豫生 |
| |
| 作者单位： | 广州白云山制药股份有限公司生化所!广州，510515，广州白云山制药股份有限公司生化所!广州，510515，广州白云山制药股份有限公司生化所!广州，510515，广州白云山制药股份有限公司生化所!广州，510515，广州白云山制药股份有限公司生化所!广州，510515 |
| |
| 摘 要： | 目的：研究小牛胸腺免疫抑制提取物对体外培养细胞生长作用。方法：采用＾３Ｈ－ＴｄＲ自发掺入细胞实验，测定细胞生长情况。结果：该提取物能抑制ＥＬ４细胞及ＣｏｎＡ诱导的小鼠胸腺细胞的生长，有量效关系，但对Ｐ８１５细胞株，Ｋ５６２细胞株细胞没有明显的抑制作用，结论：该提取物有抑制胸腺细胞生长的活性，但无细胞毒作用。
|
| 关 键 词： | 免疫提取物 药理学 细胞生长 药物作用 胸腺素 |
EFFECTS OF IMMUNOSUPPRESSIVE EXTRACTS FROM CALF THYMUS ON CELL GROWTH IN VITRO |
| |
| Zhu Shaoxuan, Wang Yusheng,Zhan Yanwei,et al. EFFECTS OF IMMUNOSUPPRESSIVE EXTRACTS FROM CALF THYMUS ON CELL GROWTH IN VITRO[J]. Journal of Guangdong Medical College, 1997, 15(4): 331-332,335 |
| |
| Authors: | Zhu Shaoxuan Wang Yusheng Zhan Yanwei et al |
| |
| Abstract: | Objective: To study the effects of the immunosuppressive extracts from calf thyrnus on cell growth in vitro. Methods:The growth of the cells was measured by 3H-TdR spontaneously incorporat-ed into DNA of the cells in vitro. Results: The immunosuppressive extracts from calf thymus showed dose-dependent inhibition on the growth of the EL4 cells and murine thymocytes induced by Con A.however,had no obvious effects on the growth of the murine P815 and human K562 cell lines. Conclusion:The immunosuppressive extracts from calf thymus can inhibit the growth of the murine thymocytes without cytotoxic effect. |
| |
| Keywords: | calf thymus/pharmacology immunosuppressive extracts/pharmacology cell growth/drug effect |
| 本文献已被 CNKI 维普 等数据库收录！ |
