枇杷叶药渣中乌索酸的提取分离

以干燥的枇杷叶药渣为材料,用7倍量90%乙醇80℃回流提取2次,每次1 h。回收溶剂后的提取物,用自制的“YCXY-1号”除杂剂除杂,生产高纯度的乌索酸。结果表明:枇杷叶药渣中含有大量三萜酸类化合物,且乌索酸含量最高。用枇杷叶药渣生产乌索酸,工艺简单,成本较低,为枇杷叶的二次开发利用提供了科学依据。

Extraction and Separatiom of Ursolic Acid from Dregs of a Decoction of Eriobotrya japonica Leaf

The chemical composition from dregs of a decoction of Eriobotrya japonica leaf was studied and the high-tech content ursolic acid from dregs of a decoction of Eriobotrya japonica was prepared after poach can produce antiinflammation and relieve a cough drug:pipa sirupus.The dry dregs of a decoction of Eriobotrya japonica leaf were extracted with 7 times of volume of alcohol at 80?℃ for 1?h and two times,and then the extracts were purified with the specific impurity remover "YCXY-1" to yield ursolic acid with high purity.A mass of triterpene acids were consisted in dregs of a decoction of Eriobotrya japonica leaf,and the content of ursolic acid was high.The production technology of ursolic acid was predigested from dregs of a decoction of Eriobotrya japonica leaf,the process was simple and the cost of production was enormously low.This research supplied scientific gist for second exploitation and utilization of Eriobotrya japonica leaf.