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牛心朴子生物碱对小鼠细胞免疫功能的影响
引用本文:张珠明,汪仁莉,何生虎.牛心朴子生物碱对小鼠细胞免疫功能的影响[J].安徽农业科学,2009,37(32):15717-15719.
作者姓名:张珠明  汪仁莉  何生虎
作者单位:宁夏大学农学院,宁夏银川,750021 
摘    要:目的]研究牛心朴子生物碱对小鼠细胞免疫功能的影响。方法]取32只小鼠,按灌药剂量分为12、24、48H影kg.bw3个试验组和1个蒸馏水对照组(0.5ml/a),连续给药30d,分别观察牛心朴子生物碱对小鼠体重、脏器指数、腹腔巨噬细胞吞噬作用及外周血T淋巴细胞数量的影响。结果]与对照组相比,饲喂3个浓度牛心朴子生物碱后小鼠体重及脏器指数、腹腔巨噬细胞的吞噬机能及外周血液中T淋巴细胞数量均有所降低。结论]在该试验条件下,一定浓度的牛心朴子生物碱对小鼠的免疫功能有抑制作用。

关 键 词:牛心朴子生物碱  细胞免疫功能  小鼠

Effects of Cynanchum komanovii alkaloid on Cellular Immune Function of Mice
ZHANG Zhu-ming et al.Effects of Cynanchum komanovii alkaloid on Cellular Immune Function of Mice[J].Journal of Anhui Agricultural Sciences,2009,37(32):15717-15719.
Authors:ZHANG Zhu-ming
Institution:ZHANG Zhu-ming et al (College of Agriculture,Ningxia University,Yinchuan,Ningxia 750021)
Abstract:Objective] The research aimed to study the effect of Cynanchum komanovii alkaloid on cellular immune function of miceMethod] 32 mice were divided into three experimental groups given medicament with daily dose of 12,24,48 mg/kg.bw and a control group infused with 0.5 ml/d distilled water in 30 days.Effects of C.komanovii alkaloid on mice body weight and viscera index,the phagocytosis of peritoneal macrophage,the T lymphocyte count of peripheral blood were observed.Result] Compared with control group,thos...
Keywords:Cynanchum komanovii alkaloid  Cellular immune function  Mice
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