噬菌体在水产品安全控制中的应用研究进展

由病原菌引起的水产品食源性疾病易引发重大公共卫生安全问题,因此控制病原菌生长至关重要。抗生素的滥用使水产品病原菌产生耐药性,因此需要寻求另一种安全有效的方法来代替抗生素,抑制病原菌。噬菌体因其能特异性裂解病原菌而受到广泛关注,被认为是最有前途的生物抑菌剂。本文在介绍噬菌体定义与作用机制的基础上,综述了噬菌体对副溶血性弧菌、沙门氏菌、溶藻弧菌与霍乱弧菌等致病菌抑制作用的研究进展,提出噬菌体应用中存在的主要问题与解决办法,并对其未来发展前景予以展望,以期为噬菌体在水产品安全控制中的研究与应用提供理论参考。

Research progress on the bacteriophage in safety control of aquatic products

Food borne diseases of aquatic products are one of the major public health and safety problems. It is very important to control the growth of pathogenic bacteria. The abuse of antibiotics leads to drug resistance of pathogens, so it is necessary to find another safe and effective method to replace antibiotics to inhibit pathogens in aquatic products. Bacteriophages have attracted much attention because of their ability to cleave pathogens and are considered to be the most promising biological bacteriostatic agent to replace antibiotics. Based on the introduction of the definition and mechanism of bacteriophage, the research progress of bacteriophage on Vibrio parahaemolyticus, Salmonella, Vibrio alginolyticus and Vibrio cholera was reviewed. The main problems and solutions in the application of bacteriophage were put forward and its future development prospect was also prospected so as to provide the theoretical reference for the research and application of bacteriophage in aquatic products.