Prior experience, antioxidants, and mitochondrial cofactors improve cognitive function in aged beagles |
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Authors: | Ikeda-Douglas Candace J Zicker Steven C Estrada Jimena Jewell Dennis E Milgram Norton W |
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Institution: | Department of Life Sciences, University of Toronto at Scarborough, Toronto, Ontario, M1C 1A4, Canada. |
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Abstract: | Results of this study support the free-radical theory of aging and demonstrated that providing higher levels of vitamin E in food resulted in higher serum vitamin E concentrations and improved performance on landmark-discrimination tasks in aged dogs. Factors other than vitamin E also contributed to the response but remain undefined. |
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