| 中药复方对衰老模型小鼠部分组织中GSH-Px活性的影响 |
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| 引用本文： | 宁鹏. 中药复方对衰老模型小鼠部分组织中GSH-Px活性的影响[J]. 动物医学进展, 2012, 0(9): 92-94 |
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| 作者姓名： | 宁鹏 |
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| 作者单位： | 青海大学农牧学院动物医学系,青海西宁810016 |
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| 摘 要： | 将60只小鼠随机分为D-半乳糖药物组、D-半乳糖对照组和对照组,每组20只。D-半乳糖药物组和D-半乳糖对照组小鼠每天背部皮下注射D-半乳糖0.15mL,对照组注射生理盐水0.2mL;D-半乳糖药物组每日灌服中药复方0.2mL,D-半乳糖对照组和对照组灌服生理盐水。15d后脱颈椎处死小鼠,取心肌、肝脏、脾脏、肺脏和肾脏,测定各组织中谷胱甘肽过氧化物酶(GSH-Px)的活性。结果表明,与D-半乳糖对照组相比,中药复方能够显著提高小鼠肝脏、肾脏中谷胱甘肽过氧化物酶(GSH-Px)的活性(P<0.05),极显著的提高肺脏、心肌和脾脏中谷胱甘肽过氧化物酶(GSH-Px)的活性(P<0.01)。说明中药复方具有较强的抗氧化作用。
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| 关 键 词： | D-半乳糖 谷胱甘肽过氧化物酶 抗氧化作用 |
Effects of Traditional Chinese Medicine Compound on the Activity of GSH-Px in Some Tissues of Aging Model Mice |
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| NING Peng. Effects of Traditional Chinese Medicine Compound on the Activity of GSH-Px in Some Tissues of Aging Model Mice[J]. Progress In Veterinary Medicine, 2012, 0(9): 92-94 |
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| Authors: | NING Peng |
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| Affiliation: | NING Peng(Veterinary Medicine Department of Agricultural and Animal Husbandry College,Qinghai University,Xining,Qinghai,810016,China) |
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| Abstract: | 60mice were divided into 3groups randomly,20mice each group.0.15mL D-galactose plus 0.2 mL traditional Chinese medicine compound,0.15mL D-galactose,and 0.2mL sodium chloride were administrated to mice every day in D-galactose and medicine group,D-galactose group and control group,respectively.Mice were sacrificed,and the heart,liver,spleen,lung and kidney were harvested.The activity of glutathion peroxidase(GSH-Px) were detected.Results showed that traditional Chinese medicine compound increased the activity of GSH-Px and had antioxidation effect. |
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| Keywords: | D-galactose GSH-Px antioxidation |
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