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氟苯尼考双混悬型乳剂对人工感染猪胸膜肺炎的临床疗效试验
引用本文:王晓赟,李孝文,孙武,罗璋,朱鑫,杨亚,孙志良.氟苯尼考双混悬型乳剂对人工感染猪胸膜肺炎的临床疗效试验[J].动物医学进展,2012,33(5):128-131.
作者姓名:王晓赟  李孝文  孙武  罗璋  朱鑫  杨亚  孙志良
作者单位:1. 湖南农业大学动物医学院,湖南长沙,410128
2. 武汉天种畜牧有限公司,湖北武汉,430344
3. 湖南新五丰股份有限公司永安分公司,湖南浏阳,411216
4. 湖南农业大学东方科技学院,湖南长沙,410128
基金项目:湖南省科技重大专项项目,长沙市科技重大专项项目
摘    要:为了探讨氟苯尼考双混悬型乳剂的临床治疗效果,确定用药方案,本试验建立体重为15kg±1.5kg的杜×长×大三元杂交商品猪胸膜肺炎人工感染病理模型。以氟苯尼考注射液为对照组,采用氟苯尼考双混悬型乳剂高(40mg/kg)、中(20mg/kg)和低(10mg/kg)剂量组进行临床治疗与观察。结果表明,氟苯尼考双混悬型乳剂高、中试验组治愈率均为100%,显著高于低剂量组和药物对照组(P<0.05)。因此,临床治疗推荐采用中(20mg/kg)剂量组,3d1次,连用2次的给药方案。

关 键 词:氟苯尼考双混悬型乳剂  人工感染  胸膜肺炎  临床疗效

Clinical Trial of Dual Suspension Emulsion of Florfenicol against Artificial Porcine Contagious Pleuropneumoia in Pigs
WANG Xiao-yun , LI Xiao-wen , SUN Wu , LUO Zhang , ZHU Xin , YANG Ya , SUN Zhi-liang.Clinical Trial of Dual Suspension Emulsion of Florfenicol against Artificial Porcine Contagious Pleuropneumoia in Pigs[J].Progress In Veterinary Medicine,2012,33(5):128-131.
Authors:WANG Xiao-yun  LI Xiao-wen  SUN Wu  LUO Zhang  ZHU Xin  YANG Ya  SUN Zhi-liang
Institution:1(1.College of Veterinary Medicine,Hunan Agricultural University,Changsha,Hunan,410128,China;2.Wuhan Tianzhong Husbandry Co.,Ltd,Wuhan,Hubei,430344,China;3.Yongan Branch,Hunan New Wellful Co.,Ltd,Liuyang,Hunan,411216,China;4.College of Orient Science &Technology,Hunan Agricultural University,Changsha,Hunan,410128,China)
Abstract:In order to explore the clinical therapeutic effect of dual suspension emulsion of florfenicol(DSEF) and determine the medication regimen,the artificial infection model of Duroc×Landrance×Yorkshire crossbred pigs of 15kg±1.5kg body weight was established.The florfenicol injection(FI) was used as the control group,and the high(40mg / kg),media(20mg / kg) and low dose(10mg / kg) groups of DSEF were used for clinical treatment and observation.The results showed that the cure rate of DSEF of high and media dose groups were 100%,and it was higher than that in low dose group and drug control group(P<0.05).Therefore,clinical treatment was recommended in 20mg / kg dose group,every three days,the two dose regimens.
Keywords:dual suspension emulsion of florfenicol  artificial infection  pleural pneumonia  clinical efficacy
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